The University of Arizona has thousands of devices to keep track of in its various datacenters. I inherited an old MS Access database someone had started in the late 90's to help manage this equipment, and transformed it into a modern web application.
The application framework I used here was CakePHP, a modern PHP based MVC framework. For the front end UI, I used the Dojo javascript framework. The result is a responsive, single window, AJAX driven web application.